EXPRESSION AND FUNCTION OF TRANSMEMBRANE-4 SUPERFAMILY (TETRASPANIN) PROTEINS IN OSTEOCLASTS: RECIPROCAL ROLES OF TSPAN-5 AND NET-6 DURING OSTEOCLASTOGENESIS

Background: Osteoclasts are bone-resorbing multinuclear polykaryons essential for bone remodeling, formed through cell fusion of mononuclear macrophage/monocyte lineage precursor cells upon stimulation by the RANK/RANKL system.Recent studies have revealed that a family of tetraspanin proteins, such as CD9, is critically involved in the cell fusion/

The 16th and 17th centuries, which are of interest to Triathlon - Accessoires me, were a period of intolerance not only from the Catholic side, but also among Protestants.However, it cannot be evaluated by contemporary standards.In the 17th century, rape and abuses were committed by both sides and were connected with the increasingly powerful posit

In the title compound, C30H31NO2, the cyclohexanone ring in the naphthalene fused-ring system adopts a half-chair conformation, presumably due to conjugation of the benzene Binaltech ring.The naphthalene ring system makes dihedral angles of 86.63 (7), 65.15 (8) and 63.18 (8)° with respect to the two methylbenz

The safe and secure containment of infectious poliovirus (PV) in facilities where live PV are handled is the condition to achieve and maintain poliomyelitis eradication.Despite precautions to minimize the risk of release of PV from such facilities to the environment, breaches of Whisk containment have already been documented.Here, we report the man

In classical Fourier optics, an optical imaging system is regarded as a linear space-invariant system, which is only an approximation.Especially in digital holography, the space-variance effect has a great impact on the image quality and cannot be ignored.Therefore, it is comprehensively investigated in this article.Theoretical analyses indicate th